This paper summarizes a feasibility study for the use of seismic base isolation for a high-rise (30 stories, 102 m) reinforced concrete building, which has planned to be constructed in Istanbul. The plausibility and effectiveness of base isolated system designs with LRB (Lead Rubber Bearing) and HRB (High-Damping Rubber Bearing) have been investigated by comparing them with the conventional fixed base model. The design of structures is based on local and international codes. Cost-effectiveness of the solutions for the selected performance levels, e.g. user comfort in terms of floor accelerations and displacements as well as architectural benefits in terms of structural members designed are explored in comparison to the conventional design.